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Guadalupe On Main

Bold Mexican flavors, craft cocktails, and a retro-modern vibe in Mesa.

4.8(5 reviews)
restaurant
$$
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About

Guadalupe On Main is a lively Mesa restaurant and bar offering Mexican-inspired dishes like mole enchiladas, duck with mole, and lobster enchiladas, paired with margaritas and mezcal cocktails. Guests praise gluten-free options, friendly, attentive staff, and a stylish, eclectic decor with live music. Bar-side seating and standout cocktails complement a welcoming atmosphere as guests savor bold flavors.

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Location

1526 E Main St, Mesa, AZ 85203, USA

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Services

Modern Mexican Dining

Enjoy elevated dishes like duck with mole, lobster enchiladas, and gluten-free options in a stylish, retro-inspired atmosphere.

Craft Cocktails & Bar

Savor expertly mixed drinks including margaritas, smoked old fashioneds, and mezcal-based cocktails at our friendly bar.

Live Music & Entertainment

Experience a vibrant ambiance with live music that enhances your dining without overwhelming conversation.

Gluten-Free Menu

Dine worry-free with a predominately gluten-free menu, including desserts, catering to celiac and dietary needs.

Brunch & Weekend Specials

Relax with no-fuss brunch offerings, games on TV, and unique dishes like green chili au graten in a casual setting.

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