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Guadalupe On Main
Bold Mexican flavors, craft cocktails, and a retro-modern vibe in Mesa.
4.8
Restaurant
$$
Bold Mexican flavors, craft cocktails, and a retro-modern vibe in Mesa.
Guadalupe On Main is a lively Mesa restaurant and bar offering Mexican-inspired dishes like mole enchiladas, duck with mole, and lobster enchiladas, paired with margaritas and mezcal cocktails. Guests praise gluten-free options, friendly, attentive staff, and a stylish, eclectic decor with live music. Bar-side seating and standout cocktails complement a welcoming atmosphere as guests savor bold flavors.
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Enjoy elevated dishes like duck with mole, lobster enchiladas, and gluten-free options in a stylish, retro-inspired atmosphere.
Savor expertly mixed drinks including margaritas, smoked old fashioneds, and mezcal-based cocktails at our friendly bar.
Experience a vibrant ambiance with live music that enhances your dining without overwhelming conversation.
Dine worry-free with a predominately gluten-free menu, including desserts, catering to celiac and dietary needs.
Relax with no-fuss brunch offerings, games on TV, and unique dishes like green chili au graten in a casual setting.
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Overall rating
Tracy Bascom
We discovered this delightful place just after Christmas. I had the featured Mole Enchiladas and wow!!! I could put that mole sauce on everything. The depth of flavor was incredible though a tiny bit spicy for me. The Blue Hawaiian cocktail was delightful. Loved the recycled Tequila bottles for water. Our server, Bria, could not have been nicer and more attentive. The restaurant itself is beautifully decorated. We decided we want to just come and sit in the bar and relax. We will visit often. 🍹💜 Only one very small complaint - Charging $2 for a one tablespoon side of crema, to offset the spiciness of my dish, seemed a little petty. 🤷♀️
michelle perry
We arrived without a reservation around 5:30pm on a Saturday. We had to wait for a table for 20 minutes but the staff were really friendly and accommodating. We ended up grabbing drinks at the bar while we waited. I ordered a Margarita which was portioned well, strong but not over powering. My husband ordered a smoked old fashioned and that was aesthetically cool but also tasted great. For dinner I ordered the Chefs Special, duck with mole, butternut squash risotto and plantains. It was honestly the best duck I ever had. The portion was large, the dish was cohesive, the added pickled red onions with the duck added the sweet and sour note to the dish. The duck was tender and fell apart upon cutting. It wasn't too greasy. The risotto had a subtle creamy butternut flavor. The plantains added a crunch. It was so yummy! My husband ordered the lobster enchiladas and the lobster was tender and the bell pepper brandy sauce was delicious! We ordered the kids bean and rice bowl with chicken for my son. He is a picky toddler and was shoveling it in his mouth. Overall the atmosphere and decor was stylish, the live music was nice and not too loud. We are definitely going back again.
Jessica Cons
Exceptional food, fantastic service and everyone is so sweet and welcoming. I appreciate that they are predominately gluten free (I have celiac), and I can eat many things on the menu including desserts, that rarely happens. We honestly love coming here because we know it’s going to be a good time and we are always well taken care of. Cannot recommend this place enough!
Alex Mayer
I was on vacation in the area and someone recommended this spot to me since I was on a quest for mole. This place delivered and it was glorious! It was a busy evening, and the team was very accommodating when I arrived. The folks behind the bar were friendly and helpful and my mezcal drink (Thirst trap) was phenomenally delish. Perfect balance of smoke and sweetness. The mole enchiladas were absolutely delicious! Flavorful , wonderful texture .. just fantastic and exactly what I wanted (especially after a long grueling hike that day!) Visually, the vibe in here is super fun and eclectic and retro. So glad I came here .. for the vibes and for the food!
Resting Warface
You have to try this place if you haven't already. Awesome drinks and attentive staff but it's the food that won me over. I'm so happy I found this place. The Elote dip is bomb! They even came up with this crazy green chili au graten, that is out of this world. It was really nice to get a no fuss meal at the bar. I'm not much of a fan of sit down places for brunch. There's not a whole of noise(which makes for a nice hangover brunch) but there's still a game on the TV. The bartenders where good at making frendly banter. Not overwhelming, but still very attentive. I can't wait to eat here again. Thanks for the good eats and great vibes!
