
Margaritas Mexican Cantina: Great food, stellar service, and refreshing margaritas in Depew.
Located at 4725 Transit Rd, Depew, NY 14043, USA Margaritas Mexican Cantina serves flavorful Mexican fare with fast, friendly service and standout margaritas, including premium options or by the pitcher. Reviews highlight delicious quesadillas, fresh guac, and a warm, welcoming atmosphere, plus clean restrooms and plenty of free parking. Attentive staff and timely meals make it a reliable choice for a satisfying dining experience.
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Freshly prepared dishes like carnitas, chile relleno, and steak quesadillas using traditional recipes.
Premium margaritas, including pineapple and dragon fruit flavors, available by the glass or pitcher.
Perfect for parties and events with customizable menus and spacious seating.
Enjoy our delicious food and drinks from the comfort of your home with convenient ordering options.
Special brunch menu featuring Mexican-inspired breakfast items and bottomless drink specials.
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Overall rating
Rich Leffler
The food here is unbelievable. The fresh guac made us see Jesus. The salsa was on point. And the service was killer. Ask for Robert A. to be your server. He ROCKS!
Charles Quagliana
We have been going here since they opened and popped in on a whim to be pleasantly surprised by great food, GREAT Service and EXCELLENT Margaritas, premium or by the pitcher! Our server was friendly and knowledgeble about the menu items. Every menu item that I have tried has been very good! I particularly enjoyed the Chille Relleno and the Carnitas. Highly recommended! The food arrived in a timely fashion and the restrooms were clean. Plenty of free parking .
blanca “Rosa” gal
So good! I ordered the steak quesadilla. Along with the pineapple and dragon fruit margarita. The service was awesome. The waiter accommodated all my requests. I would definitely recommend this place and come back again. I’m from Arizona and it’s hard to come across really good Mexican food outside of my state and this place definitely out did themselves. Thank you Jorge and Kevin !
Melissa Schlierf
I had such a great experience here! The quesadillas were absolutely delicious — perfectly cheesy, flavorful, and cooked just right. The margaritas were amazing too, super refreshing with the perfect balance of sweet and tangy. The atmosphere was warm and welcoming, and the service was excellent. I’ll definitely be coming back! Highly recommend!
Rick Roseberry
My wife picked this place based on the reviews and we weren't disappointed. Excellent food and fast service. The only downside to our experience was that the music was obnoxious and loud. I guess it's true when they say if the music is too loud, you're too old. We would go back for the food because it's excellent. If you're looking for a quiet cozy place to enjoy dinner and stimulating conversation with your fellow diners, this isn't the place.